Drug Uses
Fluoxetine is a drug used
medically in the treatment of
depression, obsessive-compulsive
disorder, bulimia nervosa,
premenstrual dysphoric disorder,
and many other disorders. It is
a psychotropic drug for oral
administration.
How
Taken
Fluoxetine usually is taken
once or twice a day. To be
effective, it should be taken
regularly. Make a habit of
taking it at the same time you
do some other daily activity. It
may be 4 weeks before you feel
any relief from your depression,
but the drug's effects should
last about 9 months after a
3-month treatment regimen. For
obsessive-compulsive disorder,
the full effect may take 5 weeks
to appear.
Warnings/Precautions
Unless you are directed to do
so by your doctor, do not take
this medication if you are
recovering from a heart attack
or if you have liver disease or
diabetes. Fluoxetine may cause
you to become drowsy or less
alert and may affect your
judgment. Therefore, driving or
operating dangerous machinery or
participating in any hazardous
activity that requires full
mental alertness is not
recommended. While taking this
medication, you may feel dizzy
or light-headed or actually
faint when getting up from a
lying or sitting position. If
getting up slowly doesn't help
or if this problem continues,
notify your doctor. If you
develop a skin rash or hives
while taking Fluoxetine,
discontinue use of the
medication and notify your
doctor immediately. Fluoxetine
should be used with caution if
you have a history of seizures.
You should discuss all of your
medical conditions with your
doctor before taking this
medication. Fluoxetine can
occasionally cause decreased
appetite and weight loss,
especially in depressed people
who are already underweight and
in those with bulimia. If you
notice changes in your weight or
appetite, tell your doctor. The
effects of Fluoxetine during
pregnancy have not been
adequately studied. If you are
pregnant or plan to become
pregnant, inform your doctor
immediately. This medication
appears in breast milk, and
breastfeeding is not recommended
while you are taking Fluoxetine.
Missed Dose
If you miss a dose of
Fluoxetine and you remember the
same day, take it as soon as
possible. If you do not remember
until the next day, skip the
missed dose and go back to your
regular dosing schedule. Do not
take 2 doses at once.
Possible Side Effects
Side effects cannot be
anticipated. If any develop or
change in intensity, inform your
doctor as soon as possible. Only
your doctor can determine if it
is safe for you to continue
taking Fluoxetine. More common
side effects may include:
Abnormal dreams, abnormal
ejaculation, abnormal vision,
anxiety, diminished sex drive,
dizziness, dry mouth, flu-like
symptoms, flushing, gas,
headache, impotence, insomnia,
itching, loss of appetite,
nausea, nervousness, rash,
sinusitis, sleepiness, sore
throat, sweating, tremors, upset
stomach, vomiting, weakness,
yawning. Less common side
effects may include: Abnormal
taste, agitation, bleeding
problems, chills, confusion, ear
pain, emotional instability,
fever, frequent urination, high
blood pressure, increased
appetite, loss of memory,
palpitations, ringing in the
ears, sleep disorders, weight
gain. In children and
adolescents, less common side
effects may also include:
Agitation, excessive menstrual
bleeding, frequent urination,
hyperactivity, mania or
hypomania (inappropriate
feelings of elation and/or rapid
thoughts), nosebleeds,
personality changes, and thirst.
A wide variety of other very
rare reactions have been
reported during Fluoxetine
therapy. If you develop any new
or unexplained symptoms, tell
your doctor without delay.
Storage
Store in a dry place at 20-25
degrees C (68-77 F).
Overdose
Any medication taken in
excess can have serious
consequences. An overdose of
Fluoxetine can be fatal. In
addition, combining Fluoxetine
with certain other drugs can
cause symptoms of overdose. If
you suspect an overdose, seek
medical attention immediately.
Common symptoms of Fluoxetine
overdose include: Nausea, rapid
heartbeat, seizures, sleepiness,
vomiting. Other symptoms of
Fluoxetine overdose include:
Coma, delirium, fainting, high
fever, irregular heartbeat, low
blood pressure, mania, rigid
muscles, sweating, stupor.
More
Information
Do not take with MAO
inhibitors or for at least two
weeks after their
discontinuation. MAO inhibitors
medications should not be taken
for at least five weeks after
discontinuing Fluoxetine. Most
medications affecting the brain
have the potential to slow
reflexes or impair judgment and
caution is advised. This
medication has not been studied
extensively in the US and
re-evaluation periodically by
your physician is advised. Check
with you pharmacist when taking
with other medications.
Disclaimer
This drug information is for
your information purposes only,
it is not intended that this
information covers all uses,
directions, drug interactions,
precautions, or adverse effects
of your medication. This is only
general information, and should
not be relied on for any
purpose. It should not be
construed as containing specific
instructions for any particular
patient.
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